Cacoa Extract



Tumeric Root

N Acetyl L Cysteine

R Alpha Lipoic Acid







All Spice

Nootropics as ingredients that fuel your mind, found in nature, and used by cultures for thousands of years to provide mental clarity and focus.


Acute Treatment with Herbal Extracts Provides Neuroprotective Benefits in In Vitro and In Vivo Stroke Models, Characterized by Reduced Ischemic Cell Death and Maintenance of Motor and Neurological Functions.

Yuji Kaneko, David J. Eve, SeongJin Yu, Hideki Shojo, Eunkyung Cate Bae, Dong-Hyuk Park, Bill Roschek, Jr., Randall S. Alberte, Paul R. Sanberg, Cyndy D. Sanberg, Paula C. Bickford, Cesar V. Borlongan

Cell Med. Author manuscript; available in PMC 2011 March 4.
Published in final edited form as: Cell Med. 2010 January 1; 1(3): 137–142

Herbal Extracts and Phytochemicals: Plant Secondary Metabolites and the Enhancement of Human Brain Function
David O. Kennedy, Emma L. Wightman, Adv Nutr. 2011 January; 2(1): 32–50.

Stuck at the bench: Potential natural neuroprotective compounds for concussion
Anthony L. Petraglia, Ethan A. Winkler, Julian E. Bailes, Surg Neurol Int. 2011; 2: 146


Potential Role of the Curry Spice Curcumin in Alzheimer’s Disease
John M. Ringman1,, Sally A. Frautschy2, Gregory M. Cole2, Donna L. Masterman3 and Jeffrey L. Cummings1,4 Current Alzheimer Research, 2005, 2, 000-000

Determining the effects of lipophilic drugs on membrane structure by solid-state NMR spectroscopy: the case of the antioxidant Curcumin.
Barry J1, Fritz M, Brender JR, Smith PE, Lee DK, Ramamoorthy A J Am Chem Soc 2009 Apr 1;131(12):4490-8.

Chemistry of curcumin and curcuminoids. Phenol Comp Food Effects Health, Tonnesen HH 1992;143-153.

Studies on curcumin and curcuminoids. XXII: Curcumin as a reducing agent and as a radical scavenger. Tonnesen HH and Greenhill JV Int J Pharmaceut 1992;87:79-87.

Effect of the long turmeric (Curcumina Longa L.) on healing peptic ulcer: a preliminary report of 10 case studies.
Prucksunand C and et al. Thai J Pharmacol 1986;8:139-151.


The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects.
Stough C1, Lloyd J, Clarke J, Downey LA, Hutchison CW, Rodgers T, Nathan PJ.
Psychopharmacology (Berl). 2001 Aug;156(4):481-4.

Examining the nootropic effects of a special extract of Bacopa monniera on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial.
Stough C1, Downey LA, Lloyd J, Silber B, Redman S, Hutchison C, Wesnes K, Nathan PJ.
Phytother Res. 2008 Dec;22(12):1629-34. doi: 10.1002/ptr.2537.

Neuroprotective effects of Bacopa monnieri (Brahmi) on novel object recognition and NMDAR1 immunodensity in the prefrontal cortex, striatum and hippocampus of sub-chronic phencyclidine rat model of schizophrenia.
Piyabhan P, Wetchateng T. J Med Assoc Thai. 2014 Aug;97 Suppl 8:S50-5.

Dietary Supplements and Sports Performance: Herbals Melvin Williams
J Int Soc Sports Nutr. 2006; 3(1): 1–6.


Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea
Yeonju Lee, Jae-Chul Jung, Soyong Jang, Jieun Kim, Zulfiqar Ali, Ikhlas A. Khan, Seikwan Oh
Evidence Based Complement Alternative Med. 2013; 2013: 514049.

Vitamin B12

Vitamin B12 and Cognitive Function: An Evidence-Based Analysis,
Health Quality Ontario
Ontario Health Technology Assess Ser. 2013; 13(23): 1–45.

Neuroenhancement with Vitamin B12—Underestimated Neurological Significance
Uwe Gröber, Klaus Kisters, Joachim Schmidt
Nutrients. 2013 December; 5(12): 5031–5045

Cognitive and psychiatric effects of vitamin B12 replacement in dementia with low serum B12 levels: a nursing home study
Christopher H. van Dyck, Jeffrey M. Lyness, Robert M. Rohrbaugh, Alan P. Siegal
Int Psychogeriatr. Author manuscript; available in PMC 2012 December 17.
Published in final edited form as: Int Psychogeriatr. 2009 February; 21(1): 138–147.


Magnesium in Disease Prevention and Overall Health
Stella Lucia Volpe
Adv Nutr. 2013 May; 4(3): 378S–383S.

Magnesium Enhances Exercise Performance via Increasing Glucose Availability in the Blood, Muscle, and Brain during Exercise
Hsuan-Ying Chen, Fu-Chou Cheng, Huan-Chuan Pan, Jaw-Cheng Hsu, Ming-Fu Wang
PLoS One. 2014; 9(1):

Magnesium Protects Cognitive Functions and Synaptic Plasticity in Streptozotocin-Induced Sporadic Alzheimer’s Model
Zhi-Peng Xu, Li Li, Jian Bao, Zhi-Hao Wang, Juan Zeng, En-Jie Liu, Xiao-Guang Li, Rong-Xi Huang, Di Gao, Meng-Zhu Li, Yao Zhang, Gong-Ping Liu, Jian-Zhi Wang
PLoS One. 2014; 9(9):

Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies
Liana C Del Gobbo, Fumiaki Imamura, Jason HY Wu, Marcia C de Oliveira Otto, Stephanie E Chiuve, Dariush Mozaffarian
Am J Clinical Nutritional. 2013 July; 98(1): 160–173
Evidence Based Med 2012;17:128-129 doi:10.1136/ebmed.2011.100310

Low serum magnesium and cardiovascular mortality in chronic heart failure: a propensity-matched study
Chris Adamopoulos, Bertram Pitt, Xuemei Sui, Thomas E Love, Faiez Zannad, Ali Ahmed
Int J Cardiol. Author manuscript; available in PMC 2010 August 21.
Published in final edited form as: Int J Cardiol. 2009 August 21; 136(3): 270–77.

Alpha Lipoic Acid

Neuroprotective Activity of Thioctic Acid in Central Nervous System Lesions Consequent to Peripheral Nerve Injury
Daniele Tomassoni, Francesco Amenta, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Innocent E. Nwankwo, Alessandra Pacini, Seyed Khosrow Tayebati
Biomed Res Int. 2013; 2013: 985093.

Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases
Marilia Brito Gomes, Carlos Antonio Negrato, Diabetol Metab Syndr. 2014; 6: 80


Health-promoting effects of Green Tea
Yasuo SUZUKI, Noriyuki MIYOSHI, Mamoru ISEMURA
Proc Jpn Acad Ser B Phys Biol Sci. 2012


Cerebrospinal fluid concentrations of N-acetylcysteine after oral administration in Parkinson’s disease.
Katz M, Won SJ, Park Y, Orr A, Jones DP, Swanson RA, Glass GA.
Parkinsonism Relat Disord. 2015 Feb 28. pii: S1353-8020(15)00075-9. doi:

Neuroprotection induced by N-acetylcysteine and selenium against traumatic brain injury-induced apoptosis and calcium entry in hippocampus of rat.
Nazıroğlu M, Senol N, Ghazizadeh V, Yürüker V. Cell Mol Neurobiol. 2014 Aug;34(6):895-903